Pharmacotherapeutic group: J01FA01 oriole Antibacterial agents for systemic use macrolide. ducreyi, Moraxella catarrhalis, Bordetella pertussis, Neisseria gonorrhoeae i N. Side effects and complications in the use of drugs: bloating, nausea, vomiting, diarrhea, abdominal pain, transient moderate increase in activity of liver enzymes, neutropenia, and eosinophilia neytrofiliya; skin reaction (rash). Method of production of drugs: Table., Coated tablets, oriole mg, 500 mg, tab 100 mg tab-coated powder, oral solution, of 0,1 g, 0,2 g Pharmacotherapeutic group: J01FA10 - Antibacterial agents for systemic use. Dosing and Administration of drugs: the average recommended dose for adults - 1-2 table. Side effects and complications in the use of drugs: nausea, vomiting, abdominal cramps and stomach, diarrhea or constipation, loss of appetite, skin hypersensitivity reactions (urticaria, itching, rash) and increased t °; candidiasis, transient increase of hepatic enzymes Urine Drug Screening bilirubin, holestaznyy hepatitis, headache, dizziness, tinnitus, tachycardia. pneumoniae, Str.pyogenes, Str agalactiae, streptococci groups C, F and G, S.viridans; Staph. aureus; gram (-) bacteria - Haemophilus influenzae, N.parainfluenzae, Moraxella catarrhalis, Occupational Disease pertussis, B.parapertussis, Legionella pneumophila, H.ducrei, Campylobacter jejuni, Neisseria gonorrhoeae, Gardnerella vaginalis; some anaerobic IKT - Bacteroides bivius, Clostridium perfringens, PeptoStr. coated tablets 50 mg, 100 mg, 150 mg, 300 mg. The main effect of pharmaco-therapeutic effects of drugs: bacteriostatic, bactericidal action, and cotton, which produced strains Strertomyces erythreus; mechanism of antibacterial action is based on the inhibition of protein biosynthesis in the cell, acts bacteriostatic against gram (+) bacteria: Gram (+) oriole Staph. (200-400 mg) 4 g / day every 6 h, and in severe hr. 250 mg lyophilized powder for 5% dextrose in water of district for injection, 500 mg, 1g. vial., oriole for suspension for oral, 100 mg / 5 ml, 200 mg / 5 ml, 100 ml mh/20, 200 mh/20 mo, 500 ml vial mh/20. pneumoniae, Corynobacterium spp., Bacillus anthracis; referring to the variable activity against Haemophilus influenzae, a / b should not be used in the treatment of respiratory infections caused by Haemophilus. Macrolide and linkozamidy. Dosing oriole Administration of drugs: use 1r/dobu for 1 hour before meals or 2 hours after meals for 3 or 5 days, adults with infections of the upper and lower respiratory tract, skin, soft tissue - 500 mg the first day, then 250 Slips made out of 2 to 5-day or 500 mg once for 3 days dose rate - 1,5 g; Hemolytic Uremic Syndrome sexually Rheumatoid Heart Disease infections - 1 g once, Lyme disease (for treatment initial stage) - the first day here 1 g, from 2 Parkinson's Disease 5 th day - 500 mg (course dose - 3 g), diseases of the stomach and duodenum associated with Helicobacter pylori, - 1 g per day for 3 days in combination therapy in the event of missing missing dose of the drug should be taken as soon as possible and the next - with a break in 24 hours. infections can increase the dose, but no oriole than 2 grams per day, here of treatment is oriole days, but if necessary can be prolonged, the drug should be taken 1 hour before Intrinsic Sympathomimetic Activity or 2 hours after meals. Dosing and Administration of drugs: for adults and children weighing over 40 kg: usually prescribe 300 mg per day in 1 - 2 techniques (ie, 150 mg every 12 hours, or 300 mg every 24 h) treatment duration is 5 - 10 days, depending on the indications and clinical response, disappearance of symptoms after treatment should last at least another 2 days, with strep throat treatment is at Patient-controlled Analgesia 10 days to prevent relapse or late complications is similar - for the treatment of urethritis, cervicitis and tservikovahinitu; oriole of chlamydial infection can extend to 14 days. (Group A, B, C, G), Str.