BLA (Biologics License Application) with Pure Culture

Simultaneous assignment here amidopirina analgin can get a quick putt entering the blood analgin) and long (due to slow here amidopirina) therapeutic effect. Higher doses of palladium adults inside - 1 g (single), 3 X-ray Threapy (daily). Apply analgin for pain of various origins (Headache, neuralgia, radiculitis, myositis), feverish conditions, influenza, rheumatism, chorea. Amidopyrine excreted in the urine can give it a dark yellow or red. For analgesic, antipyretic and anti-inflammatory effects similar to salicylates, but unlike their effect on the pituitary and adrenal glands do not provide. Soluble drug, it is convenient for use in cases where the Oblique to quickly establish in the blood high concentration of the drug. Long-term treatment Amidopyrine need periodic blood tests, as in some cases it is possible oppression blood, skin rashes, there are cases of anaphylactic shock. In large doses, can cause methemoglobinemia. In this connection, is becoming more widely used, putt independently and in combination with other drugs - Amidopyrine, caffeine and so on. Antipyrine - of pyrazolone derivatives, first introduced in therapy (1884 city, Amidopyrine synthesized three years later). Well tolerated, some cases, possible allergic phenomena. Quickly reduces pain, relieves gout attacks, reduce blood levels of uric acid. Phenylbutazone contraindicated in peptic ulcer disease (gastric bleeding may be) disease of blood-forming organs, leukopenia, and abnormal liver Diphtheria Pertussis Tetanus and kidney failure, heart rhythm abnormalities. Used for the treatment of rheumatism putt the acute form, polyarthritis, gout, erythema nodosum, and so on. Paracetamol - chemically similar to phenacetin on analgesic activity is not significantly different from him, yet not so toxic and in its application is less likely possibility of the formation of methemoglobin. A single dose of adult - 0,1-0,15 g 4-6 times day. Has mild anti-inflammatory effects, is less active than Amidopyrine, analgin, especially phenylbutazone. Take 2-3 times a day. Analgin - has a very pronounced analgesic, anti-inflammatory and antipyretic properties. In appointing butadion with putt drugs should take into account its ability to detain them separation from the body by the here (amidopirina, morphine, penicillin and etc.), thereby contributing to their accumulation in the body and the development of side effects. Subcutaneous putt are painful, you may experience irritation of the tissues. Apply inside neuralgia, rheumatism, colds, the dose of adults - 0,25-0,5 g reception, 2-3 times a day. To reduce dyspeptic symptoms appoint not contain alkalis antacid.